CHAPAS-4 resources and further information
The CHAPAS-4 trial is working to improve the second-line treatment options for children living with HIV in sub-Saharan Africa. There are growing numbers of children who need (or will need in the future) second-line antiretroviral therapy. Current second-line treatment options for children are not ideal. CHAPAS-4 is investigating new combinations of medicines for children.
Resources
- This one page document gives an overview on what the trial is, and why it is needed
- This slideset explains the trial in more detail, for clinicians
- This two page document explores the implications of the results of the ODYSSEY trial, and roll-out of dolutegravir, for CHAPAS-4
Infographics
These infographics explain the findings from the CHAPAS-4 trial after 96 weeks. These results were presented at the International AIDS Society Conference in July 2023.
- CHAPAS-4 backbone results infographic
- CHAPAS-4 anchor drug results infographic
- Results poster for children
Impact of previous trials
The team running the CHAPAS-4 trial have run a number of trials that have made a big impact on how children with HIV are treated. This one-page document summarises the difference those trials have made to children living with HIV.
This film explores the impact of previous trials run by the CHAPAS team in improving HIV treatments for children.
Chapas Clinical Trials - Developing HIV baby pills. from MRC Clinical Trials Unit at UCL on Vimeo.