C

CALM

A randomised placebo controlled trial of a cholinesterase inhibitor in the management of agitation in dementia that is unresponsive to a psychological intervention

CAMS

Cannabis in multiple sclerosis: a randomised, double blind, placebo controlled trial

Cancer: Stem cell transplantation, systematic review and aggregate data meta-analysis

Autologous stem cell transplantation for malignancy: a systematic review of the literature

CANPOP

A randomised clinical trial as proof of principle of the analgesic effectiveness of cannabinoids on post-operative pain

CANPOP Dose Finding

An open label study: would a single oral dose of a cannabis plant extract (Cannador) help to provide pain relief after surgery.

CAP

An open phase I trial of 13% cellulose acetate phthalate vaginal microbicide with randomisation to an observation control

CAP-IT

Efficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia (CAP): a randomised controlled trial

CASCADE

Concerted action on seroconversion to AIDS and death in Europe

CDIFF

An International Prospective Observational Study to Assess the Characteristics and Outcomes of Post-transplant Patients Treated for C. Difficile Infections

Cervical cancer: Chemoradiotherapy, systematic review and IPD meta-analysis

Concomitant chemoradiotherapy versus radiotherapy for cervical cancer: a systematic review and meta-analysis of individual patient data.

Cervical cancer: hydroxyurea and radiotherapy, systematic review and aggregate data meta-analysis

Concomitant hydroxyurea plus radiotherapy versus radiotherapy for carcinoma of the uterine cervix: a systematic review

Cervical cancer: Neoadjuvant chemotherapy, systematic review and IPD meta-analysis

Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data

CHAP

Co-trimoxazole as prophylaxis against opportunistic infections in HIV-infected Zambian children: a double-blind randomised placebo-controlled trial

CHAPAS-3

Children with HIV in Africa – Pharmacokinetics and adherence/acceptability of simple antiretroviral regimens

CHAPAS-4

Children with HIV in Africa – Pharmacokinetics and Acceptability of Simple second-line antiretroviral regimens

CHART (CH01)

A randomised multicentre trial of continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy

CHART (CH02)

A randomised multicentre trial of continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in head and neck cancer

CHER

Children with HIV early antiretroviral therapy

CHIPS

Collaborative HIV Paediatric Study

CHIPS+

Optimising the health of young people with HIV in their transition from paediatric to adult care

CHORUS

A large phase III multi-centre randomised trial to determine the impact of timing of surgery and chemotherapy in newly diagnosed patients with advanced epithelial ovarian, primary peritoneal or fallopian tube cancer

COIN, CR10

A three arm randomised controlled trial comparing either continuous chemotherapy plus cetuximab, or intermittent chemotherapy with standard continuous palliative combination chemotherapy with oxaliplatin and a fluoropyrimidine in first line treatment of metastatic colorectal cancer

COIN-B

A two-arm phase II randomised trial of intermittent chemotherapy plus continuous cetuximab and of intermittent chemotherapy plus intermittent cetuximab in first line treatment of patients with K-ras-normal (wild-type) metastatic colorectal cancer

Colorectal cancer: Anti-EGFR treatment, systematic review and aggregate data meta-analysis

Does anti-EGFR therapy improve outcome in advanced colorectal cancer? A systematic review and meta-analysis

CoroNerve

A collaborative initiative to describe the neurological features of COVID-19

CR09/FOCUS 2

Drug treatment for bowel cancer: making the best choices when a milder treatment is needed

CUTHIVAC 001

A Phase I clinical trial to assess the safety and immunogenicity of three HIV GTU® MultiHIV DNA immunisations administered via the Intramuscular, Intradermal and Transcutaneous routes in healthy male and female volunteers.

CUTHIVAC002

A Phase I clinical trial to assess the safety and immunogenicity of HIV DNA-C CN54ENV immunisations administered via the Intramuscular and Intradermal methods with and without electroporation followed by boosting with recombinant HIV CN54gp140 in healthy male and female volunteers.

CUTHIVTHER 001

A randomized phase I/II study to assess the safety and immunogenicity of the DNA-GTU vaccine administered by two novel methods compared to placebo in HIV-infected patients on antiretroviral therapy

COVAC1

A first-in-human clinical trial to assess the safety and immunogenicity of a self-amplifying ribonucleic acid (saRNA) vaccine encoding the S glycoprotein of SARS-CoV-2, the causative agent of COVID 19