Search Results | MRC Clinical Trials Unit at UCL

'25 at 25': Patient and Public Involvement (PPI)

For almost two decades, the MRC Clinical Trials Unit at UCL has been committed to actively involving patients and the public in all our clinical trials and studies. As part of our ‘25 at 25’ series to…

'25 at 25': OCTOPUS – speeding up new treatments for progressive MS

OCTOPUS is the first ever multi-arm multi-stage (MAMS) clinical trial in multiple sclerosis (MS). As part of our ’25 at 25’ series, we explore how the trial aims to transform the way that new treatmen…

'25 at 25': Individual participant data (IPD) meta-analysis

...ndividual participant data (IPD). As part of our ‘25 at 25’ series to celebrate the Unit’s 25th anniversary, this piece explores how our IPD meta-analyses have influenced the treatment of patients …

'25 at 25': Shortening treatment for tuberculosis

A long road to recovery lies ahead for people diagnosed with tuberculosis (TB). Treatments lasting several months can be tough for patients due to challenging side effects, the burden of daily medicat…

'25 at 25': The PRACTical trial design

As part of the MRC Clinical Trials Unit at UCL’s 25th anniversary celebrations, we highlight the Unit’s role in developing new clinical trial designs to address problems where standard trial designs a…

'25 at 25': Training and capacity strengthening

Capacity strengthening is at the core of our clinical trials and methodology work, aiming to enhance the skills of trial teams we work with across the globe, so they can deliver their own sustainable,…

'25 at 25': Conducting the first large international randomised controlled trial on tuberculosis treatment for children

... children respond to treatment. As part of our '25 at 25' series, we look back at the SHINE trial, which sought to address this evidence gap. This landmark study was the first randomised controll…

'25 at 25': Ovarian cancer screening: The UKCTOCS trial

To celebrate the 25th anniversary of the MRC Clinical Trials Unit and World Cancer Day, we highlight our work throughout the past two decades to help detect ovarian cancer earlier. This article is par…

'25 at 25': Optimising treatments for people with cancer

The cancer trials that hit the headlines tend to be about improving how long people with cancer live or delaying the disease from getting worse. This is obviously very important, particularly for type…

'25 at 25': Saving lives with early HIV treatment

During the 25th anniversary year of the MRC Clinical Trials Unit at UCL, we celebrate the fact that millions of people with HIV are now living longer, healthier lives thanks to our research. This arti…