We have been pivotal in developing novel designs, notably multi-arm multi-stage and platform, umbrella and basket protocols. 

New trial designs bring new challenges in running these trials. We share our experience of running trials with new designs in several different ways.

What have we done? 

Reviewing platform protocols: Proposed guidelines for research ethics committees (RECs) 

We ran a series of workshops for REC members in the UK, which led to the Health Research Authority updating its Standard Operating Procedures (SOPs) to reflect our recommendations on how to implement these new trial designs. 

Read the short report or a blog post from a REC member. 

Courses and clinics 

  • We run a course at the UCL Institute for Clinical Trials and Methodology on the conduct of platform trials. 
  • We run clinics on the conduct of platform trials for individuals and groups which can be arranged by contacting Sharon Love.