New methodology papers aim to improve clinical trials monitoring
Methodologists from the MRC Clinical Trials Unit at UCL have published two papers focusing on issues surrounding the monitoring of clinical trials.
14 Mar
Two-month regimen could dramatically cut length of tuberculosis treatment
A strategy of treating patients with a two-month, intensive antibiotic regimen, followed by close monitoring and re-treatment if required, was as effective at treating tuberculosis (TB) as the standard six-month regimen.…
01 Mar
MRI is cost-effective replacement for CT scans to monitor early stage testicular cancer
New findings from the TRISST study reveal that it would be cost effective to replace potentially harmful CT scans with MRI to monitor men after surgery for early stage testicular cancer.
20 Feb
New low-dose COVID-19 vaccine safely generates immune responses in 80%
A low-dose COVID-19 vaccine harnessing self-amplifying RNA (saRNA) can trigger an immune response in the majority without any serious side effects, according to phase II trial results from the COVAC1 study.
09 Feb
Cancer
Innovative clinical trial design and meta-analysis extending beyond the boundaries of single cancer types
Infections
Major international clinical trials answering questions of global public health significance
Neurodegenerative diseases
New generation of innovative multi-arm, multi stage platform clinical trials to identify and test new therapeutic treatments in neurodegenerative diseases
Methodology
Development of methods with direct impact on the design, conduct and analysis of studies
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RT @Collaboratory1: 📣 Webinar recording and slides now available: "Estimands in Cluster Randomized Trials: Choosing Analyses That Answer…