Trinh Duong, Principal Research Fellow
Trinh is a medical statistician with more than 20 years of experience. During the first half of her research career, she mainly focused on observational cohort studies and international individual patient data meta-analyses of HIV-infected children. She later transitioned to trial work, covering various disease areas.
She is currently the statistical lead on the programme TB prevention trials at the MRC CTU, which include: TB-CHAMP, assessing preventative therapy in child contacts of multidrug-resistant TB in South Africa; RID-TB, a program of work packages to improve the detection and treatment of latent TB infection in the UK; and BALANCE, evaluating the benefit-risk balance of TB preventive treatment in people with diabetes in South Africa and the Philippines.
Selected publications
Rangaka MX, Hamada Y, Duong T, et al. Evaluating the effect of short-course rifapentine-based regimens with or without enhanced behaviour-targeted treatment support on adherence and completion of treatment for latent tuberculosis infection among adults in the UK (RID-TB: Treat): protocol for an open-label, multicentre, randomised controlled trial. BMJ Open 2022;12:e057717. doi: 10.1136/bmjopen-2021-057717.
Rangaka MX, Hamada Y, Duong T, et al. A randomised controlled trial to evaluate the effectiveness of using the RD-1 based C-Tb skin test as a replacement for blood-based interferon-γ release assay for detection of, and initiation of preventive treatment for, tuberculosis infection: RID-TB - Dx study protocol. BMJ Open 2021;11:e050595. doi: 10.1136/bmjopen-2021-050595
Langley RE, Gilbert DC, Duong T, et al. Transdermal oestradiol for androgen suppression in prostate cancer: Long-term cardiovascular outcomes from the randomised Prostate Adenocarcinoma Transcutaneous Hormone (PATCH) Trials Programme. Lancet 2021;397: 581–91. doi: 10.1016/S0140-6736(21)00100-8
Gilbert D*, Duong T*, Kynaston HG, et al. (* joint first authorship). Quality of life outcomes from the PATCH trial evaluating LHRH agonists versus transdermal oestradiol for androgen suppression in advanced prostate cancer. BJU International 2017;119:667–675. doi: 10.1111/bju.13687
Duong T, Judd A, Collins IC, Doerholt K, Lyall H, Foster C, Butler K, Tookey P, Shingadia D, Menson E, Dunn DT, Gibb DM. Long-term virological outcome in children on antiretroviral therapy in the UK and Ireland. AIDS 2014;28(16):2395-405. doi:10.1097/QAD.0000000000000438.
Research Interests
- TB prevention
- Paediatric TB
- Design and analysis of clinical trials
- Individual-patient-data meta-analysis
Research Areas
UCL Profiles