Ilaria Motta, Principal Clinical Research Fellow

Ilaria is an infectious diseases physician trained at the University of Torino, Italy, with experience in managing HIV and TB infections in resource-limited settings. In 2018, she obtained her PhD in pharmacokinetics of TB drugs. From 2017 to 2023 she worked as Medical Monitor for the TB-PRACTECAL Clinical Trial with Médecins Sans Frontières (MSF) UK, and she collaborates as a clinical adviser to the EndTB/Q clinical trials with MSF-France and as TB Medical Referent for MSF-Access Campaign. She has recently completed her MSc in Public Health.

She joined the Unit in June 2023 as a Principal Clinical Research Fellow, working in PARADIGM4TB Clinical Trial, flagship study of UNITE4TB project.

Selected publications

Nyang'wa BT, Berry C, Kazounis E, Motta I, Parpieva N, Tigay Z, Solodovnikova V, Liverko I, Moodliar R, Dodd M, Ngubane N, Rassool M, McHugh TD, Spigelman M, Moore DAJ, Ritmeijer K, du Cros P, Fielding K; TB-PRACTECAL Study Collaborators. A 24-Week, All-Oral Regimen for Rifampin-Resistant Tuberculosis. N Engl J Med. 2022 Dec 22;387(25):2331-2343. doi: 10.1056/NEJMoa2117166. PMID: 36546625.

Sweeney S, Berry C, Kazounis E, Motta I, Vassall A, Dodd M, Fielding K, Nyang'wa BT. Cost-effectiveness of short, oral treatment regimens for rifampicin resistant tuberculosis. PLOS Glob Public Health. 2022 Dec 7;2(12):e0001337. doi: 10.1371/journal.pgph.0001337. PMID: 36962909; PMCID: PMC10022130.

Motta I, Calcagno A, Bonora S. Pharmacokinetics and pharmacogenetics of anti-tubercular drugs: a tool for treatment optimization? Expert Opin Drug Metab Toxicol. 2018 Jan;14(1):59-82. doi: 10.1080/17425255.2018.1416093. Epub 2017 Dec 18. PMID: 29226732.

Schepisi MS, Motta I, Dore S, Costa C, Sotgiu G, Girardi E. Tuberculosis transmission among children and adolescents in schools and other congregate settings: a systematic review. New Microbiol. 2019 Oct;41(4):282-290. Epub 2018 Sep 25. PMID: 30252926.

Motta I, Calcagno A, Baietto L, Bigliano P, Costa C, Baruffi K, Fatiguso G, D'Avolio A, Di Perri G, Bonora S. Pharmacokinetics of first-line antitubercular drugs in plasma and PBMCs. Br J Clin Pharmacol. 2017 May;83(5):1146-1148. doi: 10.1111/bcp.13196. Epub 2017 Jan 18. PMID: 28097677; PMCID: PMC5401973.

Research Interests

  • Pharmacokinetics of TB drugs
  • Platform Clinical Trials
  • Tuberculosis treatment (drug-susceptible and drug resistant)
  • HIV infection and opportunistic infections

Research Areas