FOCUS4
Specific randomised trials based on molecular test results
FOCUS4 is a molecularly stratified, multi-site randomised trial programme for patients with colorectal cancer which opened to recruitment in the UK in 2014.
FOCUS4 is designed to identify and register eligible patients, perform a set of molecular tests on a sample of their tumour and then enrol them into a specific randomised trial based on the results of the molecular tests. Each molecularly stratified trial aims to compare a novel intervention to placebo or standard care.